7PK4

Tick salivary cystatin Ricistatin in complex with cathepsin V

Summary for 7PK4

• Entry DOI: 10.2210/pdb7pk4/pdb
• Descriptor: Cathepsin L2, Putative salivary cystatin, GLYCEROL, ... (6 entities in total)
• Functional Keywords: hydrolase, complex, cystatin, tick
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 37460.76

Authors

Busa, M.,Mares, M. (deposition date: 2021-08-25, release date: 2022-12-14, Last modification date: 2024-01-31)

• Primary citation: Martins, L.A.,Busa, M.,Chlastakova, A.,Kotal, J.,Berankova, Z.,Stergiou, N.,Jmel, M.A.,Schmitt, E.,Chmelar, J.,Mares, M.,Kotsyfakis, M.; Protease-bound structure of Ricistatin provides insights into the mechanism of action of tick salivary cystatins in the vertebrate host.; Cell.Mol.Life Sci., 80:339-339, 2023; PubMed: 37898573; DOI: 10.1007/s00018-023-04993-4

Experimental method

X-RAY DIFFRACTION (1.92 Å)