7PK4
Tick salivary cystatin Ricistatin in complex with cathepsin V
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cathepsin L2 | polymer | 222 | 24139.0 | 1 | UniProt (O60911) Pfam (PF00112) | Homo sapiens (Human) | Cathepsin U,Cathepsin V |
| 2 | B (B) | Putative salivary cystatin | polymer | 116 | 12751.1 | 1 | UniProt (A0A0K8RMA7) Pfam (PF00031) | Ixodes ricinus (Common tick Acarus ricinus) | |
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D, E, F, G, I... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 5 | H (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A: 0 - 221 (UniProt: O60911)
B: 1 - 115 (UniProt: A0A0K8RMA7)
| PDB | External Database | Details |
|---|---|---|
| Ser 25 | Cys 138 | engineered mutation |
| Gln 108 | Asn 221 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36890.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 570.6 | |
| All* | Total formula weight | 37460.8 |
