7PC0

GABA-A receptor bound by a-Cobratoxin

This is a non-PDB format compatible entry.

Summary for 7PC0

• Entry DOI: 10.2210/pdb7pc0/pdb
• EMDB information: 13315
• Descriptor: Megabody 25, 2-acetamido-2-deoxy-beta-D-glucopyranose, HISTAMINE, ... (13 entities in total)
• Functional Keywords: neurotransmission, toxin, gaba, membrane protein
• Biological source: Lama glama; More
• Total number of polymer chains: 8
• Total formula weight: 320538.65

Authors

Kasaragod, V.B.,Miller, P.S. (deposition date: 2021-08-03, release date: 2022-02-09, Last modification date: 2022-03-02)

• Primary citation: Kasaragod, V.B.,Mortensen, M.,Hardwick, S.W.,Wahid, A.A.,Dorovykh, V.,Chirgadze, D.Y.,Smart, T.G.,Miller, P.S.; Mechanisms of inhibition and activation of extrasynaptic alpha beta GABA A receptors.; Nature, 602:529-533, 2022; PubMed: 35140402; DOI: 10.1038/s41586-022-04402-z

Experimental method

ELECTRON MICROSCOPY (3 Å)