Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (F) | Megabody 25 | polymer | 522 | 56329.6 | 1 | Lama glama | ||
| 2 | B (A) | Gamma-aminobutyric acid receptor subunit alpha-1 | polymer | 368 | 41991.1 | 1 | UniProt (P14867) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | GABA(A) receptor subunit alpha-1 |
| 3 | C, D, E (B, C, E) | Gamma-aminobutyric acid receptor subunit beta-3 | polymer | 451 | 51615.1 | 3 | UniProt (P28472) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | GABA(A) receptor subunit beta-3 |
| 4 | F (D) | Gamma-aminobutyric acid receptor subunit alpha-1 | polymer | 411 | 47059.6 | 1 | UniProt (P14867) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | GABA(A) receptor subunit alpha-1 |
| 5 | G, H (K, L) | Alpha-cobratoxin | polymer | 71 | 7842.1 | 2 | UniProt (P01391) Pfam (PF21947) | Naja kaouthia (monocled cobra) | Alpha-CT,Alpha-CbT,Alpha-Cbtx,Alpha-Ctx,Alpha-elapitoxin-Nk2a,Alpha-EPTX-Nk2a,Long neurotoxin 1,Siamensis 3 |
| 6 | I (G) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G55220VL) | |||
| 7 | J (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 8 | K (I) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G09724ZC) | |||
| 9 | L (J) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 10 | M, P, Q, R (A, C, E, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 11 | N (B) | HISTAMINE | non-polymer | 111.1 | 1 | Chemie (HSM) | |||
| 12 | O (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 13 | S (D) | HEXANE | non-polymer | 86.2 | 1 | Chemie (HEX) |
Sequence modifications
A: 5 - 312 (UniProt: P14867)
A: 391 - 429 (UniProt: P14867)
B, C, E: 8 - 307 (UniProt: P28472)
B, C, E: 422 - 448 (UniProt: P28472)
D: 5 - 312 (UniProt: P14867)
D: 391 - 429 (UniProt: P14867)
| PDB | External Database | Details |
|---|---|---|
| Gln 2 | - | expression tag |
| Pro 3 | - | expression tag |
| Ser 4 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 313 | - | linker |
| Gln 314 | - | linker |
| Pro 315 | - | linker |
| Ala 316 | - | linker |
| Arg 317 | - | linker |
| Ala 318 | - | linker |
| Ala 319 | - | linker |
| Gly 430 | - | expression tag |
| Thr 431 | - | expression tag |
| Thr 432 | - | expression tag |
| Glu 433 | - | expression tag |
| Ser 434 | - | expression tag |
| Thr 435 | - | expression tag |
| Gln 436 | - | expression tag |
| Val 437 | - | expression tag |
| Ala 438 | - | expression tag |
| Pro 439 | - | expression tag |
| Ala 440 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gln 1 | - | expression tag |
| Ser 2 | - | expression tag |
| Val 3 | - | expression tag |
| Asn 4 | - | expression tag |
| Asp 5 | - | expression tag |
| Pro 6 | - | expression tag |
| Gly 7 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 308 | - | linker |
| Gln 308 | - | linker |
| Pro 308 | - | linker |
| Ala 308 | - | linker |
| Gly 308 | - | linker |
| Thr 308 | - | linker |
| Ala 308 | - | linker |
| Asp 308 | - | linker |
| Leu 308 | - | linker |
| Glu 308 | - | linker |
| Asp 308 | - | linker |
| Asn 308 | - | linker |
| Trp 308 | - | linker |
| Glu 308 | - | linker |
| Thr 308 | - | linker |
| Leu 308 | - | linker |
| Asn 308 | - | linker |
| Asp 308 | - | linker |
| Asn 308 | - | linker |
| Leu 308 | - | linker |
| Lys 308 | - | linker |
| Val 308 | - | linker |
| Ile 308 | - | linker |
| Glu 308 | - | linker |
| Lys 308 | - | linker |
| Ala 308 | - | linker |
| Asp 308 | - | linker |
| Asn 309 | - | linker |
| Ala 309 | - | linker |
| Ala 309 | - | linker |
| Gln 309 | - | linker |
| Val 309 | - | linker |
| Lys 309 | - | linker |
| Asp 309 | - | linker |
| Ala 309 | - | linker |
| Leu 309 | - | linker |
| Thr 309 | - | linker |
| Lys 309 | - | linker |
| Met 309 | - | linker |
| Arg 309 | - | linker |
| Ala 309 | - | linker |
| Ala 309 | - | linker |
| Ala 309 | - | linker |
| Leu 309 | - | linker |
| Asp 309 | - | linker |
| Ala 309 | - | linker |
| Gln 309 | - | linker |
| Lys 309 | - | linker |
| Ala 309 | - | linker |
| Thr 309 | - | linker |
| Pro 309 | - | linker |
| Pro 309 | - | linker |
| Lys 309 | - | linker |
| Leu 310 | - | linker |
| Glu 310 | - | linker |
| Asp 310 | - | linker |
| Lys 310 | - | linker |
| Ser 310 | - | linker |
| Pro 310 | - | linker |
| Asp 310 | - | linker |
| Ser 310 | - | linker |
| Pro 310 | - | linker |
| Glu 310 | - | linker |
| Met 310 | - | linker |
| Lys 310 | - | linker |
| Asp 310 | - | linker |
| Phe 310 | - | linker |
| Arg 310 | - | linker |
| His 310 | - | linker |
| Gly 310 | - | linker |
| Phe 310 | - | linker |
| Asp 310 | - | linker |
| Ile 310 | - | linker |
| Leu 310 | - | linker |
| Val 310 | - | linker |
| Gly 310 | - | linker |
| Gln 310 | - | linker |
| Ile 310 | - | linker |
| Asp 310 | - | linker |
| Asp 311 | - | linker |
| Ala 311 | - | linker |
| Leu 311 | - | linker |
| Lys 311 | - | linker |
| Leu 311 | - | linker |
| Ala 311 | - | linker |
| Asn 311 | - | linker |
| Glu 311 | - | linker |
| Gly 311 | - | linker |
| Lys 311 | - | linker |
| Val 311 | - | linker |
| Lys 311 | - | linker |
| Glu 311 | - | linker |
| Ala 311 | - | linker |
| Gln 311 | - | linker |
| Ala 311 | - | linker |
| Ala 311 | - | linker |
| Ala 311 | - | linker |
| Glu 311 | - | linker |
| Gln 311 | - | linker |
| Leu 311 | - | linker |
| Lys 311 | - | linker |
| Thr 311 | - | linker |
| Thr 311 | - | linker |
| Arg 311 | - | linker |
| Asn 311 | - | linker |
| Ala 312 | - | linker |
| Tyr 312 | - | linker |
| Ile 312 | - | linker |
| Gln 312 | - | linker |
| Lys 312 | - | linker |
| Tyr 312 | - | linker |
| Leu 312 | - | linker |
| Thr 312 | - | linker |
| Gly 312 | - | linker |
| Arg 419 | - | linker |
| Ala 420 | - | linker |
| Ala 421 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Met -52 | - | initiating methionine |
| Asp -51 | - | expression tag |
| Glu -50 | - | expression tag |
| Lys -49 | - | expression tag |
| Thr -48 | - | expression tag |
| Thr -47 | - | expression tag |
| Gly -46 | - | expression tag |
| Trp -45 | - | expression tag |
| Arg -44 | - | expression tag |
| Gly -43 | - | expression tag |
| Gly -42 | - | expression tag |
| His -41 | - | expression tag |
| Val -40 | - | expression tag |
| Val -39 | - | expression tag |
| Glu -38 | - | expression tag |
| Gly -37 | - | expression tag |
| Leu -36 | - | expression tag |
| Ala -35 | - | expression tag |
| Gly -34 | - | expression tag |
| Glu -33 | - | expression tag |
| Leu -32 | - | expression tag |
| Glu -31 | - | expression tag |
| Gln -30 | - | expression tag |
| Leu -29 | - | expression tag |
| Arg -28 | - | expression tag |
| Ala -27 | - | expression tag |
| Arg -26 | - | expression tag |
| Leu -25 | - | expression tag |
| Glu -24 | - | expression tag |
| His -23 | - | expression tag |
| His -22 | - | expression tag |
| Pro -21 | - | expression tag |
| Gln -20 | - | expression tag |
| Gly -19 | - | expression tag |
| Gln -18 | - | expression tag |
| Arg -17 | - | expression tag |
| Glu -16 | - | expression tag |
| Pro -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Tyr -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Ile -11 | - | expression tag |
| Pro -10 | - | expression tag |
| Thr -9 | - | expression tag |
| Thr -8 | - | expression tag |
| Glu -7 | - | expression tag |
| Asn -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Tyr -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Thr 0 | - | expression tag |
| Gly 1 | - | expression tag |
| Gln 2 | - | expression tag |
| Pro 3 | - | expression tag |
| Ser 4 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 313 | - | linker |
| Gln 314 | - | linker |
| Pro 315 | - | linker |
| Ala 316 | - | linker |
| Arg 317 | - | linker |
| Ala 318 | - | linker |
| Ala 319 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 315909.9 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 3481.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1147.6 | |
| All* | Total formula weight | 320538.7 |
