7P57

VSG2 mutant structure lacking the calcium binding pocket

7P57 の概要

• エントリーDOI: 10.2210/pdb7p57/pdb
• 関連するPDBエントリー: 1VSG 7P56 7P59 7P5A 7P5B 7P5D
• 分子名称: Variant surface glycoprotein MITAT 1.2, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: variant surface glycoprotein, coat, trypanosoma brucei, african trypanosome, immune evasion, antigenic variation, calcium binding, calcium, membrane protein
• 由来する生物種: Trypanosoma brucei brucei
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 51720.07

構造登録者

Gkeka, A.,Aresta-Branco, F.,Stebbins, C.E.,Papavasiliou, F.N. (登録日: 2021-07-14, 公開日: 2022-07-27, 最終更新日: 2024-02-07)

• 主引用文献: Gkeka, A.,Aresta-Branco, F.,Triller, G.,Vlachou, E.P.,van Straaten, M.,Lilic, M.,Olinares, P.D.B.,Perez, K.,Chait, B.T.,Blatnik, R.,Ruppert, T.,Verdi, J.P.,Stebbins, C.E.,Papavasiliou, F.N.; Immunodominant surface epitopes power immune evasion in the African trypanosome.; Cell Rep, 42:112262-112262, 2023; PubMed: 36943866; DOI: 10.1016/j.celrep.2023.112262

実験手法

X-RAY DIFFRACTION (1.961 Å)