7OUV

Crystal structure of human filamin C domains 14-15 cardiovascular disease causing mutation S1624L

Summary for 7OUV

• Entry DOI: 10.2210/pdb7ouv/pdb
• Descriptor: Isoform 2 of Filamin-C (2 entities in total)
• Functional Keywords: ig-like, mechanosensing, muscle protein, heart, structural protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 43014.21

Authors

Mlynek, G.,Djinovic-Carugo, K. (deposition date: 2021-06-13, release date: 2022-06-22, Last modification date: 2024-05-01)

• Primary citation: Mlynek, G.,Djinovic-Carugo, K.; Analysis and prediction of pathogenic missense variants in human filamin C; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)