7OPO

RSK2 N-terminal kinase domain in complex with ORF45

Summary for 7OPO

Entry DOI	10.2210/pdb7opo/pdb
Descriptor	Ribosomal protein S6 kinase alpha-3, Protein ORF45, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
Functional Keywords	orf45, rsk2, rsk, rsk2 ntk, viral modulation, mapkapk, kaposi's sarcoma-associated herpesvirus, viral protein, vf-motif
Biological source	Homo sapiens (Human) More
Total number of polymer chains	12
Total formula weight	261221.63
Authors	Sok, P.,Remenyi, A.,Alexa, A.,Poti, A. (deposition date: 2021-06-01, release date: 2022-02-02, Last modification date: 2024-01-31)
Primary citation	Alexa, A.,Sok, P.,Gross, F.,Albert, K.,Kobori, E.,Poti, A.L.,Gogl, G.,Bento, I.,Kuang, E.,Taylor, S.S.,Zhu, F.,Ciliberto, A.,Remenyi, A. A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host. Nat Commun, 13:472-472, 2022 Cited by PubMed: 35078976 DOI: 10.1038/s41467-022-28109-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.75 Å)

Structure validation