7OPO

RSK2 N-terminal kinase domain in complex with ORF45

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004672	molecular_function	protein kinase activity
A	0004674	molecular_function	protein serine/threonine kinase activity
A	0005524	molecular_function	ATP binding
A	0006468	biological_process	protein phosphorylation
C	0004672	molecular_function	protein kinase activity
C	0004674	molecular_function	protein serine/threonine kinase activity
C	0005524	molecular_function	ATP binding
C	0006468	biological_process	protein phosphorylation
E	0004672	molecular_function	protein kinase activity
E	0004674	molecular_function	protein serine/threonine kinase activity
E	0005524	molecular_function	ATP binding
E	0006468	biological_process	protein phosphorylation
G	0004672	molecular_function	protein kinase activity
G	0004674	molecular_function	protein serine/threonine kinase activity
G	0005524	molecular_function	ATP binding
G	0006468	biological_process	protein phosphorylation
I	0004672	molecular_function	protein kinase activity
I	0004674	molecular_function	protein serine/threonine kinase activity
I	0005524	molecular_function	ATP binding
I	0006468	biological_process	protein phosphorylation
K	0004672	molecular_function	protein kinase activity
K	0004674	molecular_function	protein serine/threonine kinase activity
K	0005524	molecular_function	ATP binding
K	0006468	biological_process	protein phosphorylation

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	27
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGQGSFGKVFlVkkisgsdarql.......YAMK

Chain	Residue	Details
A	LEU74-LYS100

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site_id	PS00108
Number of Residues	13
Details	PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IiYrDLKpeNILL

Chain	Residue	Details
A	ILE189-LEU201

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site_id	PS00284
Number of Residues	11
Details	SERPIN Serpins signature. VEVNHPFIVkL

Chain	Residue	Details
A	VAL123-LEU133

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	MOD_RES: Phosphoserine; by host TBK1 and IKKE => ECO:0000269|PubMed:11943871, ECO:0000269|PubMed:22787218

Chain	Residue	Details
B	SER41
D	SER41
F	SER41
H	SER41
J	SER41
L	SER41

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00159

Chain	Residue	Details
A	LEU74
I	LYS100
K	LEU74
K	LYS100
A	LYS100
C	LEU74
C	LYS100
E	LEU74
E	LYS100
G	LEU74
G	LYS100
I	LEU74

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site_id	SWS_FT_FI3
Number of Residues	6
Details	MOD_RES: Phosphoserine; by PDPK1 => ECO:0000250|UniProtKB:P18654, ECO:0000305

Chain	Residue	Details
A	SER227
C	SER227
E	SER227
G	SER227
I	SER227
K	SER227

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