7OPO

RSK2 N-terminal kinase domain in complex with ORF45

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I...	Ribosomal protein S6 kinase alpha-3	polymer	317	36338.1	6	UniProt (P51812) Pfam (PF00069) In PDB	Homo sapiens (Human)	S6K-alpha-3,90 kDa ribosomal protein S6 kinase 3,p90-RSK 3,p90RSK3,Insulin-stimulated protein kinase 1,ISPK-1,MAP kinase-activated protein kinase 1b,MAPK-activated protein kinase 1b,MAPKAP kinase 1b,MAPKAPK-1b,Ribosomal S6 kinase 2,RSK-2,pp90RSK2
2	B, D, F, H, J...	Protein ORF45	polymer	63	6692.7	6	UniProt (F5HDE4) In PDB	Human herpesvirus 8 (HHV-8 Kaposi's sarcoma-associated herpesvirus)
3	A, C, E, G, I...	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	6	Chemie (ANP)
4		water	water		18.0	47	Chemie (HOH)

Sequence modifications

A, C, E, G, I, K: 39 - 351 (UniProt: P51812)

PDB	External Database	Details
Gly 35	-	expression tag
Ser 36	-	expression tag
Ala 37	-	expression tag
Ser 38	-	expression tag

B, D, F, H, J, L: 16 - 76 (UniProt: F5HDE4)

PDB	External Database	Details
Gly 14	-	expression tag
Ser 15	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	258184.5
Non-Polymers*	Number of molecules	6
	Total formula weight	3037.2
All*	Total formula weight	261221.6

*Water molecules are not included.