7OPM

Phosphorylated ERK2 in complex with ORF45

Summary for 7OPM

Entry DOI	10.2210/pdb7opm/pdb
Descriptor	Mitogen-activated protein kinase 1, synthetic ERK2 inhibitor peptide, Protein ORF45, ... (6 entities in total)
Functional Keywords	mapk, erk2, phosphorylated erk2, orf45, kaposi's sarcoma-associated herpesvirus, fxfp-motif, viral protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	46365.17
Authors	Sok, P.,Remenyi, A.,Alexa, A.,Poti, A. (deposition date: 2021-06-01, release date: 2022-02-02, Last modification date: 2024-01-31)
Primary citation	Alexa, A.,Sok, P.,Gross, F.,Albert, K.,Kobori, E.,Poti, A.L.,Gogl, G.,Bento, I.,Kuang, E.,Taylor, S.S.,Zhu, F.,Ciliberto, A.,Remenyi, A. A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host. Nat Commun, 13:472-472, 2022 Cited by PubMed: 35078976 DOI: 10.1038/s41467-022-28109-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45 Å)

Structure validation