7OPM
Phosphorylated ERK2 in complex with ORF45
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 1 | polymer | 364 | 41906.9 | 1 | UniProt (P28482) Pfam (PF00069) | Homo sapiens (Human) | MAP kinase 1,MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAP kinase 2,MAPK 2 |
| 2 | B (B) | synthetic ERK2 inhibitor peptide | polymer | 18 | 2276.7 | 1 | synthetic construct | p28 | |
| 3 | C (C) | Protein ORF45 | polymer | 14 | 1593.9 | 1 | UniProt (F5HDE4) | Human herpesvirus 8 | |
| 4 | D (A) | 1-[4-(hydroxymethyl)-1H-pyrazolo[4,3-c]pyridin-6-yl]-3-[(1S)-1-phenylethyl]urea | non-polymer | 311.3 | 1 | Chemie (08G) | |||
| 5 | E, F, G (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | H, I, J (A, B, C) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A: 1 - 360 (UniProt: P28482)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 45777.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 587.6 | |
| All* | Total formula weight | 46365.2 |
