7OP9
Purine nucleoside phosphorylase(DeoD-type) from H. pylori with 2,6-dichloropurine
Summary for 7OP9
Entry DOI | 10.2210/pdb7op9/pdb |
Related | 7OOY 7OOZ |
Descriptor | Purine nucleoside phosphorylase DeoD-type, 2,6-bis(chloranyl)-7H-purine, IMIDAZOLE, ... (5 entities in total) |
Functional Keywords | inhibitor, complex, transferase |
Biological source | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) |
Total number of polymer chains | 12 |
Total formula weight | 313851.04 |
Authors | Narczyk, M.,Stefanic, Z. (deposition date: 2021-05-31, release date: 2022-05-04, Last modification date: 2024-01-31) |
Primary citation | Narczyk, M.,Wojtys, M.I.,Lescic Asler, I.,Zinic, B.,Luic, M.,Jagusztyn-Krynicka, E.K.,Stefanic, Z.,Bzowska, A. Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium. J Enzyme Inhib Med Chem, 37:1083-1097, 2022 Cited by PubMed: 35437103DOI: 10.1080/14756366.2022.2061965 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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