7OP0

Crystal structure of complement C5 in complex with chemically synthesized K92 knob domain.

Summary for 7OP0

• Entry DOI: 10.2210/pdb7op0/pdb
• Descriptor: Complement C5 alpha chain, Complement C5 beta chain, K92chemFE, ... (6 entities in total)
• Functional Keywords: complement c5, c5, ultralong, ultra-long, knob domain., immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 190491.42

Authors

Macpherson, A.,van der Elsen, J.M.H.,Schulze, M.E.,Birtley, J.R. (deposition date: 2021-05-28, release date: 2022-04-06, Last modification date: 2024-01-31)

• Primary citation: Macpherson, A.,Birtley, J.R.,Broadbridge, R.J.,Brady, K.,Schulze, M.E.D.,Tang, Y.,Joyce, C.,Saunders, K.,Bogle, G.,Horton, J.,Kelm, S.,Taylor, R.D.,Franklin, R.J.,Selby, M.D.,Laabei, M.,Wonfor, T.,Hold, A.,Stanley, P.,Vadysirisack, D.,Shi, J.,van den Elsen, J.,Lawson, A.D.G.; The Chemical Synthesis of Knob Domain Antibody Fragments.; Acs Chem.Biol., 16:1757-1769, 2021; PubMed: 34406751; DOI: 10.1021/acschembio.1c00472

Experimental method

X-RAY DIFFRACTION (2.57 Å)