7OP0
Crystal structure of complement C5 in complex with chemically synthesized K92 knob domain.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004866 | molecular_function | endopeptidase inhibitor activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006954 | biological_process | inflammatory response |
| A | 0006956 | biological_process | complement activation |
| B | 0004866 | molecular_function | endopeptidase inhibitor activity |
Functional Information from PROSITE/UniProt
| site_id | PS01177 |
| Number of Residues | 35 |
| Details | ANAPHYLATOXIN_1 Anaphylatoxin domain signature. CCydGacvnnde.TCEqraarisl.GprCikafte.CC |
| Chain | Residue | Details |
| A | CYS698-CYS732 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:18536718, ECO:0007744|PDB:3CU7, ECO:0007744|PDB:3KLS, ECO:0007744|PDB:3KM9 |
| Chain | Residue | Details |
| A | ASN741 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:18536718, ECO:0000269|PubMed:21217642, ECO:0007744|PDB:3CU7, ECO:0007744|PDB:3KLS, ECO:0007744|PDB:3KM9 |
| Chain | Residue | Details |
| A | ASN911 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN1115 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952 |
| Chain | Residue | Details |
| A | ASN1630 |
