7OAT
Structural basis for targeted p97 remodelling by ASPL as prerequisite for p97 trimethylation by METTL21D
Summary for 7OAT
Entry DOI | 10.2210/pdb7oat/pdb |
Descriptor | Tether containing UBX domain for GLUT4, Transitional endoplasmic reticulum ATPase, Protein-lysine methyltransferase METTL21D, ... (8 entities in total) |
Functional Keywords | p97, aaa+ atpase, aspl, mettl21d, vcp-kmt, vcp, methylation, remodelling, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 101509.79 |
Authors | Petrovic, S.,Heinemann, U.,Roske, Y. (deposition date: 2021-04-20, release date: 2022-08-03, Last modification date: 2024-02-07) |
Primary citation | Petrovic, S.,Roske, Y.,Rami, B.,Phan, M.H.Q.,Panakova, D.,Heinemann, U. Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D. Proc.Natl.Acad.Sci.USA, 120:e2208941120-e2208941120, 2023 Cited by PubMed: 36656859DOI: 10.1073/pnas.2208941120 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.995 Å) |
Structure validation
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