7NSG

Structure of human excitatory amino acid transporter 3 (EAAT3) in complex with HIP-B

Summary for 7NSG

• Entry DOI: 10.2210/pdb7nsg/pdb
• EMDB information: 12566
• Descriptor: Excitatory amino acid transporter 3, (+)-3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole-6-carboxylic acid, (-)-3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole-6-carboxylic acid, ... (5 entities in total)
• Functional Keywords: glutamate, aspartate transporter, cysteine, inhibitor complex, membrane protein, structural genomics, structural genomics consortium, sgc
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 174103.79

Authors

Baronina, A.,Pike, A.C.W.,Yu, X.,Dong, Y.Y.,Shintre, C.A.,Tessitore, A.,Chu, A.,Rotty, B.,Venkaya, S.,Mukhopadhyay, S.M.M.,Borkowska, O.,Chalk, R.,Shrestha, L.,Burgess-Brown, N.A.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Han, S.,Carpenter, E.P.,Structural Genomics Consortium (SGC) (deposition date: 2021-03-05, release date: 2022-03-16, Last modification date: 2024-07-10)

• Primary citation: Baronina, A.,Pike, A.C.W.,Yu, X.,Dong, Y.Y.,Shintre, C.A.,Tessitore, A.,Chu, A.,Rotty, B.,Venkaya, S.,Mukhopadhyay, S.M.M.,Borkowska, O.,Chalk, R.,Shrestha, L.,Burgess-Brown, N.A.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Han, S.,Carpenter, E.P.; Structure of human excitatory amino acid transporter 3 (EAAT3) in complex with HIP-B; TO BE PUBLISHED,

Experimental method

ELECTRON MICROSCOPY (3.34 Å)