7NSG
Structure of human excitatory amino acid transporter 3 (EAAT3) in complex with HIP-B
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Excitatory amino acid transporter 3 | polymer | 487 | 53252.9 | 3 | UniProt (P43005) Pfam (PF00375) In PDB | Homo sapiens (Human) | Excitatory amino-acid carrier 1,Neuronal and epithelial glutamate transporter,Sodium-dependent glutamate/aspartate transporter 3,Solute carrier family 1 member 1 |
2 | A, B, C | (+)-3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole-6-carboxylic acid | non-polymer | 172.1 | 3 | Chemie (UR5) | |||
3 | A, B, C | (-)-3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole-6-carboxylic acid | non-polymer | 172.1 | 3 | Chemie (UR8) | |||
4 | A, B, C | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 3 | Chemie (Y01) | |||
5 | C, A, B | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 15 | Chemie (PC1) |
Sequence modifications
A, B, C: 1 - 480 (UniProt: P43005)
PDB | External Database | Details |
---|---|---|
Arg 42 | Ser 42 | engineered mutation |
Val 92 | Leu 92 | engineered mutation |
Ala 481 | - | expression tag |
Glu 482 | - | expression tag |
Asn 483 | - | expression tag |
Leu 484 | - | expression tag |
Tyr 485 | - | expression tag |
Phe 486 | - | expression tag |
Gln 487 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 159758.6 | |
Non-Polymers* | Number of molecules | 24 |
Total formula weight | 14345.2 | |
All* | Total formula weight | 174103.8 |