7NOZ
Structure of the nanobody stablized properdin bound alternative pathway proconvertase C3b:FB:FP
Summary for 7NOZ
Entry DOI | 10.2210/pdb7noz/pdb |
Descriptor | Complement C3 beta chain, alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total) |
Functional Keywords | protease, complement, cascade, proconvertase, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 317060.38 |
Authors | Lorenzen, J.,Pedersen, D.V.,Andersen, G.R. (deposition date: 2021-02-26, release date: 2022-07-27, Last modification date: 2024-01-31) |
Primary citation | Lorentzen, J.,Pedersen, D.V.,Gadeberg, T.A.F.,Andersen, G.R. Structure determination of an unstable macromolecular complex enabled by nanobody-peptide bridging. Protein Sci., 31:e4432-e4432, 2022 Cited by PubMed: 36173177DOI: 10.1002/pro.4432 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.9 Å) |
Structure validation
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