7NJ1
CryoEM structure of the human Separase-Securin complex
Summary for 7NJ1
Entry DOI | 10.2210/pdb7nj1/pdb |
EMDB information | 12369 |
Descriptor | Separin, Securin (2 entities in total) |
Functional Keywords | pseudosubstrate heat repeat caspase cell cycle, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 259662.81 |
Authors | Yu, J.,Raia, P.,Ghent, C.M.,Raisch, T.,Sadian, Y.,Barford, D.,Raunser, S.,Morgan, D.O.,Boland, A. (deposition date: 2021-02-14, release date: 2021-08-04, Last modification date: 2021-08-18) |
Primary citation | Yu, J.,Raia, P.,Ghent, C.M.,Raisch, T.,Sadian, Y.,Cavadini, S.,Sabale, P.M.,Barford, D.,Raunser, S.,Morgan, D.O.,Boland, A. Structural basis of human separase regulation by securin and CDK1-cyclin B1. Nature, 596:138-142, 2021 Cited by PubMed: 34290405DOI: 10.1038/s41586-021-03764-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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