7MHZ
Human Hedgehog acyltransferase (HHAT) in complex with a palmitoylated Hedgehog peptide product and a Fab antibody fragment
Summary for 7MHZ
Entry DOI | 10.2210/pdb7mhz/pdb |
EMDB information | 23837 |
Descriptor | Sonic hedgehog protein N-product peptide, Protein-cysteine N-palmitoyltransferase HHAT, 3H02 Fab heavy chain, ... (8 entities in total) |
Functional Keywords | mboat, goat, porcupine, acyl transferase, membrane protein, membrane enzyme, er, palmitoyl-coa, transferase-immune system complex, transferase/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 148470.20 |
Authors | Long, S.B.,Jiang, Y. (deposition date: 2021-04-16, release date: 2021-06-16, Last modification date: 2024-10-09) |
Primary citation | Jiang, Y.,Benz, T.L.,Long, S.B. Substrate and product complexes reveal mechanisms of Hedgehog acylation by HHAT. Science, 372:1215-1219, 2021 Cited by PubMed: 34112694DOI: 10.1126/science.abg4998 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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