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7MHZ

Human Hedgehog acyltransferase (HHAT) in complex with a palmitoylated Hedgehog peptide product and a Fab antibody fragment

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
Sonic hedgehog protein N-product peptidepolymer8750.81UniProt (Q15465)Homo sapiensShhN,Shh N-terminal processed signaling domains,ShhNp
2B
(A)
Protein-cysteine N-palmitoyltransferase HHATpolymer49357358.71UniProt (Q5VTY9)
Pfam (PF03062)
Homo sapiens (Human)Hedgehog acyltransferase,Melanoma antigen recognized by T-cells 2,MART-2,Skinny hedgehog protein 1
3C
(O)
3H02 Fab heavy chainpolymer46251307.91Mus musculus
4D
(P)
3H02 Fab light chainpolymer20722868.91Mus musculus
5E
(B)
PALMITIC ACIDnon-polymer256.41Chemie (PLM)
6F
(A)
PROTOPORPHYRIN IX CONTAINING FEnon-polymer616.51Chemie (HEM)
7G, H, I
(A)
Palmitoyl-CoAnon-polymer1005.93Chemie (PKZ)
8J, K, L, M, N...
(A)
Digitoninnon-polymer1229.310Chemie (AJP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight132286.3
Non-Polymers*Number of molecules15
Total formula weight16183.9
All*Total formula weight148470.2
*Water molecules are not included.

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PDB entries from 2024-11-13

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