7LF4

Structure of importin a3 bound to the p50- and p65-NLSs

Summary for 7LF4

Entry DOI	10.2210/pdb7lf4/pdb
Descriptor	Importin subunit alpha-3, Nuclear factor NF-kappa-B p105 subunit, Transcription factor p65 (3 entities in total)
Functional Keywords	nuclear import, importin alpha 3, nls, nf-kb, p50, p65, protein transport
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	125243.82
Authors	Florio, T.J.,Lokareddy, R.K.,Cingolani, G. (deposition date: 2021-01-15, release date: 2022-01-19, Last modification date: 2023-10-25)
Primary citation	Florio, T.J.,Lokareddy, R.K.,Yeggoni, D.P.,Sankhala, R.S.,Ott, C.A.,Gillilan, R.E.,Cingolani, G. Differential recognition of canonical NF-kappa B dimers by Importin alpha 3. Nat Commun, 13:1207-1207, 2022 Cited by PubMed: 35260573 DOI: 10.1038/s41467-022-28846-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation