7LB3
Crystal structure of the second bromodomain (BD2) of human TAF1 bound to ZS1-580
Summary for 7LB3
Entry DOI | 10.2210/pdb7lb3/pdb |
Descriptor | Transcription initiation factor TFIID subunit 1, 4-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-(S-methylsulfonimidoyl)cyclopropyl]pyrimidin-2-yl}-1H-indazole, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | bromodomain, taf1, non-bet, bet, kinase inhibitor, atr, dual brd-kinase, transferase, gene regulation |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 16357.39 |
Authors | Karim, M.R.,Schonbrunn, E. (deposition date: 2021-01-07, release date: 2022-01-12, Last modification date: 2023-10-18) |
Primary citation | Karim, M.R.,Schonbrunn, E. Crystal structure of the second bromodomain (BD2) of human TAF1 bound to ZS1-580 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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