7L9X
Structure of VPS4B in complex with an allele-specific covalent inhibitor
Summary for 7L9X
Entry DOI | 10.2210/pdb7l9x/pdb |
Descriptor | Vacuolar protein sorting-associated protein 4B, N-{3-[(8-phenyl[1,2,4]triazolo[1,5-a]pyridin-2-yl)amino]phenyl}propanamide, SULFATE ION, ... (4 entities in total) |
Functional Keywords | chemical inhibitor, hydrolase, atpase, aaa superfamily, protein transport |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 50039.73 |
Authors | Grasso, M.,Cupido, T.,Kapoor, T.M. (deposition date: 2021-01-05, release date: 2021-04-14, Last modification date: 2023-10-18) |
Primary citation | Cupido, T.,Jones, N.H.,Grasso, M.J.,Pisa, R.,Kapoor, T.M. A chemical genetics approach to examine the functions of AAA proteins. Nat.Struct.Mol.Biol., 28:388-397, 2021 Cited by PubMed: 33782614DOI: 10.1038/s41594-021-00575-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.81 Å) |
Structure validation
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