7L5B
Crystallographic structure of neutralizing antibody 2-15 in complex with SARS-CoV-2 spike receptor-binding Domain (RBD).
Summary for 7L5B
Entry DOI | 10.2210/pdb7l5b/pdb |
Descriptor | Spike protein S1, 2-15 Heavy chain, 2-15 Light Chain (3 entities in total) |
Functional Keywords | spike protein s1, receptor binding protein sars cov-2, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 3 |
Total formula weight | 73986.70 |
Authors | Reddem, E.R.,Shapiro, L. (deposition date: 2020-12-21, release date: 2021-02-10, Last modification date: 2023-10-18) |
Primary citation | Rapp, M.,Guo, Y.,Reddem, E.R.,Yu, J.,Liu, L.,Wang, P.,Cerutti, G.,Katsamba, P.,Bimela, J.S.,Bahna, F.A.,Mannepalli, S.M.,Zhang, B.,Kwong, P.D.,Huang, Y.,Ho, D.D.,Shapiro, L.,Sheng, Z. Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class. Cell Rep, 35:108950-108950, 2021 Cited by PubMed: 33794145DOI: 10.1016/j.celrep.2021.108950 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.18 Å) |
Structure validation
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