7L5B

Crystallographic structure of neutralizing antibody 2-15 in complex with SARS-CoV-2 spike receptor-binding Domain (RBD).

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Spike protein S1	polymer	239	26898.3	1	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	S glycoprotein,E2,Peplomer protein,Spike glycoprotein
2	B (H)	2-15 Heavy chain	polymer	227	24333.3	1		Homo sapiens
3	C (L)	2-15 Light Chain	polymer	216	22755.1	1		Homo sapiens

Sequence modifications

A: 319 - 537 (UniProt: P0DTC2)

PDB	External Database	Details
Ala 316	-	expression tag
Pro 317	-	expression tag
Arg 318	-	expression tag
Gly 538	-	expression tag
Ser 539	-	expression tag
Leu 540	-	expression tag
Glu 541	-	expression tag
Val 542	-	expression tag
Leu 543	-	expression tag
Phe 544	-	expression tag
Gln 545	-	expression tag
Gly 546	-	expression tag
Pro 547	-	expression tag
Gly 548	-	expression tag
His 549	-	expression tag
His 550	-	expression tag
His 551	-	expression tag
His 552	-	expression tag
His 553	-	expression tag
His 554	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	73986.7
All*	Total formula weight	73986.7

*Water molecules are not included.