7KX0

Crystal structure of the CD27:CD70 co-stimulatory complex

7KX0 の概要

• エントリーDOI: 10.2210/pdb7kx0/pdb
• 分子名称: CD70 antigen, CD27 antigen, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: complex, tnf, costimulation, trimer, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 96511.78

構造登録者

Maben, Z.,Liu, W.,Mosyak, L.,Chaparro-Riggers, J. (登録日: 2020-12-02, 公開日: 2021-09-08, 最終更新日: 2023-10-18)

• 主引用文献: Liu, W.,Maben, Z.,Wang, C.,Lindquist, K.C.,Li, M.,Rayannavar, V.,Lopez Armenta, I.,Nager, A.,Pascua, E.,Dominik, P.K.,Oyen, D.,Wang, H.,Roach, R.C.,Allan, C.M.,Mosyak, L.,Chaparro-Riggers, J.; Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex.; J.Biol.Chem., 297:101102-101102, 2021; PubMed: 34419446; DOI: 10.1016/j.jbc.2021.101102

実験手法

X-RAY DIFFRACTION (2.69 Å)