7KR5
Cryo-EM structure of the CRAC channel Orai in an open conformation; H206A gain-of-function mutation in complex with an antibody
Summary for 7KR5
Entry DOI | 10.2210/pdb7kr5/pdb |
EMDB information | 23002 |
Descriptor | Calcium release-activated calcium channel protein 1, 19B5 Fab heavy chain, 19B5 Fab light chain, ... (4 entities in total) |
Functional Keywords | ion channel, calcium, soce, crac, eukaryotic, open structure, membrane protein, amphiboles, cryo-em, transport protein-immune system complex, transport protein/immune system |
Biological source | Drosophila melanogaster (Fruit fly) More |
Total number of polymer chains | 12 |
Total formula weight | 302422.40 |
Authors | |
Primary citation | Hou, X.,Outhwaite, I.R.,Pedi, L.,Long, S.B. Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformation. Elife, 9:-, 2020 Cited by PubMed: 33252040DOI: 10.7554/eLife.62772 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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