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7KQF

The internal aldimine form of the wild-type Tryptophan Synthase from Salmonella in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site at 1.47 Angstrom resolution

7KQF の概要
エントリーDOI10.2210/pdb7kqf/pdb
関連するPDBエントリー4HT3 6C73 7JHW 7JLL 7K0B 7KH6 7KMC
分子名称Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, ... (10 entities in total)
機能のキーワードinhibitor, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
由来する生物種Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
詳細
タンパク質・核酸の鎖数2
化学式量合計73937.50
構造登録者
Hilario, E.,Dunn, M.F.,Mueller, L.J. (登録日: 2020-11-15, 公開日: 2021-11-24, 最終更新日: 2023-10-18)
主引用文献Hilario, E.,Dunn, M.F.,Mueller, L.J.
The internal aldimine form of the wild-type Tryptophan Synthase from Salmonella in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site at 1.47 Angstrom resolution.
To be Published,
実験手法
X-RAY DIFFRACTION (1.47 Å)
構造検証レポート
Validation report summary of 7kqf
検証レポート(詳細版)ダウンロードをダウンロード

222036

件を2024-07-03に公開中

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