7JHW

The internal aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site and Cesium ion at the metal coordination site

Summary for 7JHW

• Entry DOI: 10.2210/pdb7jhw/pdb
• Related: 4HT3 4XUG 6C73
• Descriptor: Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, ... (9 entities in total)
• Functional Keywords: lyase, inhibitor complex, tryptophan synthase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); More
• Total number of polymer chains: 2
• Total formula weight: 74494.56

Authors

Hilario, E.,Mueller, L.J.,Dunn, M.F. (deposition date: 2020-07-21, release date: 2021-07-28, Last modification date: 2023-10-18)

• Primary citation: Hilario, E.,Mueller, L.J.,Dunn, M.F.; The internal aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site and Cesium ion at the metal coordination site.; To be Published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)