7KH6

1.45 Angstrom resolution internal aldimine crystal structure of the beta-Q114A mutant of TryptophanSynthase in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site

Summary for 7KH6

• Entry DOI: 10.2210/pdb7kh6/pdb
• Related: 4HT3 6C73 6WX3 7JHW 7JLL 7K0B
• Descriptor: Tryptophan synthase alpha chain, Tryptophan synthase beta chain, DIMETHYL SULFOXIDE, ... (10 entities in total)
• Functional Keywords: inhibitor, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); More
• Total number of polymer chains: 2
• Total formula weight: 74048.18

Authors

Hilario, E.,Dunn, M.F.,Mueller, L.J. (deposition date: 2020-10-20, release date: 2021-10-27, Last modification date: 2023-10-18)

• Primary citation: Hilario, E.,Dunn, M.F.,Mueller, L.J.; 1.45 Angstrom resolution internal aldimine crystal structure of the beta-Q114A mutant of Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site.; To be Published,

Experimental method

X-RAY DIFFRACTION (1.45 Å)