7KH6
1.45 Angstrom resolution internal aldimine crystal structure of the beta-Q114A mutant of TryptophanSynthase in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site
Summary for 7KH6
Entry DOI | 10.2210/pdb7kh6/pdb |
Related | 4HT3 6C73 6WX3 7JHW 7JLL 7K0B |
Descriptor | Tryptophan synthase alpha chain, Tryptophan synthase beta chain, DIMETHYL SULFOXIDE, ... (10 entities in total) |
Functional Keywords | inhibitor, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) More |
Total number of polymer chains | 2 |
Total formula weight | 74048.18 |
Authors | Hilario, E.,Dunn, M.F.,Mueller, L.J. (deposition date: 2020-10-20, release date: 2021-10-27, Last modification date: 2023-10-18) |
Primary citation | Hilario, E.,Dunn, M.F.,Mueller, L.J. 1.45 Angstrom resolution internal aldimine crystal structure of the beta-Q114A mutant of Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site. To be Published, |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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