7KES
Crystal structure of meta-AAC0038, an environmental aminoglycoside resistance enzyme, mutant H168A in complex with apramycin and CoA
7KES の概要
エントリーDOI | 10.2210/pdb7kes/pdb |
関連するPDBエントリー | 5HT0 6mmz 6mn0 6mn1 6mn2 |
分子名称 | Aminoglycoside N(3)-acetyltransferase, GLYCEROL, COENZYME A, ... (6 entities in total) |
機能のキーワード | antibiotic_nat family, acetyltransferase, aminoglycoside, antibiotic resistance, metagenome, soil, csgid, transferase, center for structural genomics of infectious diseases, national institute of allergy and infectious diseases, niaid, transferase-antibiotic complex, transferase/antibiotic |
由来する生物種 | uncultured bacterium |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 60326.75 |
構造登録者 | Stogios, P.J.,Skarina, T.,Michalska, K.,Xu, Z.,Yim, V.,Savchenko, A.,Joachimiak, A.,Satchell, K.J.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2020-10-12, 公開日: 2020-10-21, 最終更新日: 2023-10-18) |
主引用文献 | Stogios, P.J.,Bordeleau, E.,Xu, Z.,Skarina, T.,Evdokimova, E.,Chou, S.,Diorio-Toth, L.,D'Souza, A.W.,Patel, S.,Dantas, G.,Wright, G.D.,Savchenko, A. Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family. Commun Biol, 5:263-263, 2022 Cited by PubMed: 35338238DOI: 10.1038/s42003-022-03219-w 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.36 Å) |
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