7KD6

Insulin Receptor L1-CR plus alphaCT fragment in co-complex with Fv 83-7 and single-chain insulin SCI-b

Summary for 7KD6

• Entry DOI: 10.2210/pdb7kd6/pdb
• Related: 6VEP
• Descriptor: Single-chain Insulin SCI-b, GLYCEROL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• Functional Keywords: insulin receptor single-chain insulin antibody fv module insulin micro-receptor, signaling protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 20
• Total formula weight: 295389.59

Authors

Lawrence, M.C.,Menting, J.G. (deposition date: 2020-10-08, release date: 2021-10-13, Last modification date: 2023-10-18)

• Primary citation: Smith, N.A.,Menting, J.G.,Weiss, M.A.,Lawrence, M.C.,Smith, B.J.; Single-chain insulin analogs threaded by the insulin receptor alpha CT domain.; Biophys.J., 2022; PubMed: 36181268; DOI: 10.1016/j.bpj.2022.09.038

Experimental method

X-RAY DIFFRACTION (2.6 Å)