7JZ0

Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1) and S-Adenosyl-L-homocysteine (SAH).

Summary for 7JZ0

Descriptor2'-O-methyltransferase, Non-structural protein 10, RNA (5'-D(*(M7G))-R(P*(A2M)P*UP*U)-3'), ... (9 entities in total)
Functional Keywordsstructural genomics, center for structural genomics of infectious diseases, csgid, nsp16, nsp10, complex, viral protein, sah, cap-1, viral protein-rna complex, viral protein/rna
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
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Total number of polymer chains6
Total molecular weight103538.77
Authors
Primary citation
Minasov, G.,Shuvalova, L.,Rosas-Lemus, M.,Kiryukhina, O.,Brunzelle, J.S.,Satchell, K.J.F.,Center for Structural Genomics of Infectious Diseases (CSGID)
Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1) and S-Adenosyl-L-homocysteine (SAH).
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.15 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone 0.202200 17.5% 0.28MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
169436
PDB entries from 2020-09-30