7JZ0
Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1) and S-Adenosyl-L-homocysteine (SAH).
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004483 | molecular_function | methyltransferase cap1 activity |
| B | 0003723 | molecular_function | RNA binding |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0019079 | biological_process | viral genome replication |
| C | 0004483 | molecular_function | methyltransferase cap1 activity |
| D | 0003723 | molecular_function | RNA binding |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0019079 | biological_process | viral genome replication |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 588 |
| Details | Domain: {"description":"Nidovirus-type SAM-dependent 2'-O-MTase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01300","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 48 |
| Details | Repeat: {"description":"LRR 9","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01300","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01297","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
