7JZ0
Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1) and S-Adenosyl-L-homocysteine (SAH).
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004483 | molecular_function | mRNA (nucleoside-2'-O-)-methyltransferase activity |
| B | 0003723 | molecular_function | RNA binding |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0019079 | biological_process | viral genome replication |
| C | 0004483 | molecular_function | mRNA (nucleoside-2'-O-)-methyltransferase activity |
| D | 0003723 | molecular_function | RNA binding |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0019079 | biological_process | viral genome replication |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01297 |
| Chain | Residue | Details |
| B | CYS4327 | |
| D | CYS4330 | |
| D | HIS4336 | |
| D | CYS4343 | |
| D | CYS4370 | |
| D | CYS4373 | |
| D | CYS4381 | |
| D | CYS4383 | |
| B | CYS4330 | |
| B | HIS4336 | |
| B | CYS4343 | |
| B | CYS4370 | |
| B | CYS4373 | |
| B | CYS4381 | |
| B | CYS4383 | |
| D | CYS4327 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by 3CL-PRO => ECO:0000250|UniProtKB:P0C6V3 |
| Chain | Residue | Details |
| B | GLN4392 | |
| D | GLN4392 |
