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7JZ0

Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1) and S-Adenosyl-L-homocysteine (SAH).

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C2'-O-methyltransferasepolymer30033556.42UniProt (P0DTD1)
Pfam (PF06460)
In PDB
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)NSP16
2B, DNon-structural protein 10polymer14115004.12UniProt (P0DTD1)
Pfam (PF09401)
In PDB
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)NSP10
3E, FRNA (5'-D(*(M7G))-R(P*(A2M)P*UP*U)-3')polymer72338.42Severe acute respiratory syndrome coronavirus 2
4A, CS-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.42Chemie (SAH)
5A, CSODIUM IONnon-polymer23.04Chemie (NA)
6C, ACHLORIDE IONnon-polymer35.57Chemie (CL)
7C, A, BFORMIC ACIDnon-polymer46.08Chemie (FMT)
8D, BZINC IONnon-polymer65.44Chemie (ZN)
9waterwater18.0393Chemie (HOH)
Sequence modifications
A, C: 6799 - 7096 (UniProt: P0DTD1)
PDBExternal DatabaseDetails
Ser 6797-expression tag
Asn 6798-expression tag
B, D: 4254 - 4392 (UniProt: P0DTD1)
PDBExternal DatabaseDetails
Ser 4252-expression tag
Asn 4253-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight101798.0
Non-Polymers*Number of molecules25
Total formula weight1738.8
All*Total formula weight103536.8
*Water molecules are not included.

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PDB entries from 2024-09-18

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