7JHP

Crystal structure of HRas in complex with the Ras-binding and cysteine-rich domains of CRaf-kinase

Summary for 7JHP

Entry DOI	10.2210/pdb7jhp/pdb
Descriptor	GTPase HRas, RAF proto-oncogene serine/threonine-protein kinase, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (6 entities in total)
Functional Keywords	ras, raf, rbd, crd, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	34862.48
Authors	Cookis, T.,Mattos, C. (deposition date: 2020-07-21, release date: 2020-08-05, Last modification date: 2023-10-18)
Primary citation	Cookis, T.,Mattos, C. Crystal Structure Reveals the Full Ras-Raf Interface and Advances Mechanistic Understanding of Raf Activation. Biomolecules, 11:-, 2021 Cited by PubMed: 34356620 DOI: 10.3390/biom11070996 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.766 Å)

Structure validation