7F5H

The crystal structure of RBD-Nanobody complex, DL28 (SC4)

Summary for 7F5H

• Entry DOI: 10.2210/pdb7f5h/pdb
• Descriptor: SARS-CoV-2 Spike Receptor-Binding Domain (RBD), Nanobody DL28, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: nanobody, rbd, neutralizing antibody, sars-cov-2, receptor-binding domain, receptor-binding motif, rbm distortion, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 4
• Total formula weight: 80475.59

Authors

Luo, Z.P.,Li, T.,Lai, Y.,Zhou, Y.,Tan, J.,Li, D. (deposition date: 2021-06-22, release date: 2022-06-29, Last modification date: 2023-11-29)

• Primary citation: Li, T.,Zhou, B.,Luo, Z.,Lai, Y.,Huang, S.,Zhou, Y.,Li, Y.,Gautam, A.,Bourgeau, S.,Wang, S.,Bao, J.,Tan, J.,Lavillette, D.,Li, D.; Structural Characterization of a Neutralizing Nanobody With Broad Activity Against SARS-CoV-2 Variants.; Front Microbiol, 13:875840-875840, 2022; PubMed: 35722331; DOI: 10.3389/fmicb.2022.875840

Experimental method

X-RAY DIFFRACTION (3 Å)