7ET1

Cryo-EM structure of the gastric proton pump K791S/E820D/Y340N/E936V/Y799W mutant in K+-occluded (K+)E2-AlF state

Summary for 7ET1

• Entry DOI: 10.2210/pdb7et1/pdb
• EMDB information: 31294
• Descriptor: Sodium/potassium-transporting ATPase subunit alpha, Potassium-transporting ATPase subunit beta, MAGNESIUM ION, ... (9 entities in total)
• Functional Keywords: p-type atpase, gastric proton pump, membrane protein, primary transporter, transporter
• Biological source: Sus scrofa (Pig); More
• Total number of polymer chains: 2
• Total formula weight: 142960.29

Authors

Abe, K. (deposition date: 2021-05-12, release date: 2021-09-01, Last modification date: 2022-03-16)

• Primary citation: Abe, K.,Yamamoto, K.,Irie, K.,Nishizawa, T.,Oshima, A.; Gastric proton pump with two occluded K + engineered with sodium pump-mimetic mutations.; Nat Commun, 12:5709-5709, 2021; PubMed: 34588453; DOI: 10.1038/s41467-021-26024-1

Experimental method

ELECTRON MICROSCOPY (2.6 Å)