7ECA
Crystal structure of the Keap1 complex with a peptide base on ETGE motif.
Summary for 7ECA
Entry DOI | 10.2210/pdb7eca/pdb |
Descriptor | Kelch-like ECH-associated protein 1, LEU-ASP-GLU-GLU-THR-GLY-GLU-PHE-LEU-PRO, SULFATE ION, ... (4 entities in total) |
Functional Keywords | nrf2, oxidative stress, cancer, cytosolic protein |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 40821.12 |
Authors | |
Primary citation | Cheng, L.,Wang, H.,Li, S.,Liu, Z.,Wang, C. New insights into the mechanism of Keap1-Nrf2 interaction based on cancer-associated mutations. Life Sci, 282:119791-119791, 2021 Cited by PubMed: 34229009DOI: 10.1016/j.lfs.2021.119791 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.00006351943 Å) |
Structure validation
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