7ECA

Crystal structure of the Keap1 complex with a peptide base on ETGE motif.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Kelch-like ECH-associated protein 1	polymer	333	36850.3	1	UniProt (Q9Z2X8) Pfam (PF01344)	Mus musculus (Mouse)	Cytosolic inhibitor of Nrf2,INrf2
2	B (B)	LEU-ASP-GLU-GLU-THR-GLY-GLU-PHE-LEU-PRO	polymer	25	2914.2	1	UniProt (Q60795)	Mus musculus
3	C, D, E, F, G... (A)	SULFATE ION	non-polymer		96.1	11	Chemie (SO4)
4	N, O (A, B)	water	water		18.0	160	Chemie (HOH)

Sequence modifications

A: 309 - 624 (UniProt: Q9Z2X8)

PDB	External Database	Details
Met 292	-	initiating methionine
Gly 293	-	expression tag
His 294	-	expression tag
His 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
Glu 300	-	expression tag
Asn 301	-	expression tag
Leu 302	-	expression tag
Tyr 303	-	expression tag
Phe 304	-	expression tag
Gln 305	-	expression tag
Gly 306	-	expression tag
His 307	-	expression tag
Met 308	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	39764.4
Non-Polymers*	Number of molecules	11
	Total formula weight	1056.7
All*	Total formula weight	40821.1

*Water molecules are not included.