7E8M
Crystal structure of SARS-CoV-2 antibody P2C-1F11 with mutated RBD
Summary for 7E8M
Entry DOI | 10.2210/pdb7e8m/pdb |
Descriptor | Spike protein S1, antibody P2C-1F11 heavy chain, antibody P2C-1F11 light chain, ... (5 entities in total) |
Functional Keywords | sars-cov-2 spike, receptor binding domain, antibody, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
Total number of polymer chains | 3 |
Total formula weight | 68255.12 |
Authors | Wang, X.Q.,Zhang, L.Q.,Ge, J.W.,Wang, R.K.,Lan, J. (deposition date: 2021-03-02, release date: 2021-05-26, Last modification date: 2023-11-29) |
Primary citation | Wang, R.,Zhang, Q.,Ge, J.,Ren, W.,Zhang, R.,Lan, J.,Ju, B.,Su, B.,Yu, F.,Chen, P.,Liao, H.,Feng, Y.,Li, X.,Shi, X.,Zhang, Z.,Zhang, F.,Ding, Q.,Zhang, T.,Wang, X.,Zhang, L. Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species. Immunity, 54:1611-1621.e5, 2021 Cited by PubMed: 34166623DOI: 10.1016/j.immuni.2021.06.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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