7DXG
Structure of SAR7334-bound TRPC6 at 2.9 angstrom
Summary for 7DXG
Entry DOI | 10.2210/pdb7dxg/pdb |
EMDB information | 30908 |
Descriptor | Short transient receptor potential channel 6, ZINC ION, CALCIUM ION, ... (7 entities in total) |
Functional Keywords | trpc6, trpc, fsgs, sar7334, channel, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 441178.58 |
Authors | |
Primary citation | Guo, W.,Tang, Q.,Wei, M.,Kang, Y.,Wu, J.X.,Chen, L. Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites. Neuron, 110:1023-1035.e5, 2022 Cited by PubMed: 35051376DOI: 10.1016/j.neuron.2021.12.023 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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