7CLZ
Crystal structure of Alp1U W187F/Y247F in complex with fluostatin C
Summary for 7CLZ
Entry DOI | 10.2210/pdb7clz/pdb |
Related | 6KXH |
Descriptor | Putative hydrolase, Fluostatin C, SODIUM ION, ... (6 entities in total) |
Functional Keywords | substrate, complex, biosynthesis, hydrolase |
Biological source | Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL B-2516) |
Total number of polymer chains | 4 |
Total formula weight | 149662.36 |
Authors | |
Primary citation | Zhang, L.,De, B.C.,Zhang, W.,Mandi, A.,Fang, Z.,Yang, C.,Zhu, Y.,Kurtan, T.,Zhang, C. Mutation of an atypical oxirane oxyanion hole improves regioselectivity of the alpha / beta-fold epoxide hydrolase Alp1U. J.Biol.Chem., 295:16987-16997, 2020 Cited by PubMed: 33004437DOI: 10.1074/jbc.RA120.015563 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.10001009432 Å) |
Structure validation
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