7C8E

Crystal Structure of 14-3-3 epsilon with 9J10 peptide

Summary for 7C8E

Entry DOI	10.2210/pdb7c8e/pdb
Descriptor	14-3-3 protein epsilon, 9J10, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywords	signaling protein, phosphopeptide binding, peptide complex, protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	63511.88
Authors	Mathivanan, S.,Sudhakar, S.,Bairy, S.,Kamariah, N.,Venkitaraman, A. (deposition date: 2020-05-30, release date: 2021-06-02, Last modification date: 2023-11-29)
Primary citation	Emery, A.,Hardwick, B.S.,Crooks, A.T.,Milech, N.,Watt, P.M.,Mithra, C.,Kumar, V.,Giridharan, S.,Sadasivam, G.,Mathivanan, S.,Sudhakar, S.,Bairy, S.,Bharatham, K.,Hurakadli, M.A.,Prasad, T.K.,Kamariah, N.,Muellner, M.,Coelho, M.,Torrance, C.J.,McKenzie, G.J.,Venkitaraman, A.R. Target identification for small-molecule discovery in the FOXO3a tumor-suppressor pathway using a biodiverse peptide library. Cell Chem Biol, 28:1602-1615.e9, 2021 Cited by PubMed: 34111400 DOI: 10.1016/j.chembiol.2021.05.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.16 Å)

Structure validation