7BBD
Crystal structure of monoubiquitinated TRIM21 RING (Ub-RING) In complex with ubiquitin charged Ube2N (Ube2N~Ub) and Ube2V2
Summary for 7BBD
Entry DOI | 10.2210/pdb7bbd/pdb |
Descriptor | Polyubiquitin-B,E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 variant 2, ... (6 entities in total) |
Functional Keywords | e3 ubiquitin ligase, e2 conjugating enzyme, ubiquitin chain elongation, ligase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 61198.92 |
Authors | Kiss, L.,Neuhaus, D.,James, L.C. (deposition date: 2020-12-17, release date: 2021-01-27, Last modification date: 2024-01-31) |
Primary citation | Kiss, L.,Clift, D.,Renner, N.,Neuhaus, D.,James, L.C. RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination. Nat Commun, 12:1220-1220, 2021 Cited by PubMed: 33619271DOI: 10.1038/s41467-021-21443-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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