7B9K

Cryo-EM structure of the dihydrolipoyl transacetylase cubic core of the E. coli pyruvate dehydrogenase complex including lipoyl domains

Summary for 7B9K

• Entry DOI: 10.2210/pdb7b9k/pdb
• EMDB information: 12104
• Descriptor: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (1 entity in total)
• Functional Keywords: multienzyme complexes, oxoacid dehydrogenase complexes, lipoic acid, dihydrolipoyllysine, transferase
• Biological source: Escherichia coli (strain K12)
• Total number of polymer chains: 24
• Total formula weight: 1592716.87

Authors

Skerlova, J.,Stenmark, P. (deposition date: 2020-12-14, release date: 2021-08-11, Last modification date: 2021-10-06)

• Primary citation: Skerlova, J.,Berndtsson, J.,Nolte, H.,Ott, M.,Stenmark, P.; Structure of the native pyruvate dehydrogenase complex reveals the mechanism of substrate insertion.; Nat Commun, 12:5277-5277, 2021; PubMed: 34489474; DOI: 10.1038/s41467-021-25570-y

Experimental method

ELECTRON MICROSCOPY (3.16 Å)