7B0I
Structure of a minimal SF3B core in complex with spliceostatin A (form II)
Summary for 7B0I
Entry DOI | 10.2210/pdb7b0i/pdb |
Related | 5IFE 6EN4 |
Descriptor | Splicing factor 3B subunit 3,Splicing factor 3B subunit 3,Splicing factor 3B subunit 3, Splicing factor 3B subunit 5, Splicing factor 3B subunit 1, ... (7 entities in total) |
Functional Keywords | sf3b, pre-mrna splicing, splicing modulator, spliceostatin a, splicing |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 219877.62 |
Authors | |
Primary citation | Cretu, C.,Gee, P.,Liu, X.,Agrawal, A.,Nguyen, T.V.,Ghosh, A.K.,Cook, A.,Jurica, M.,Larsen, N.A.,Pena, V. Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12:4491-4491, 2021 Cited by PubMed: 34301950DOI: 10.1038/s41467-021-24741-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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