7AK5

Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2 A

Summary for 7AK5

• Entry DOI: 10.2210/pdb7ak5/pdb
• EMDB information: 11810
• Descriptor: NADH-ubiquinone oxidoreductase chain 3, NADH-ubiquinone oxidoreductase chain 6, NADH-ubiquinone oxidoreductase chain 4L, ... (54 entities in total)
• Functional Keywords: deactive complex i, oxidoreductase
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 45
• Total formula weight: 1063250.64

Authors

Yin, Z.,Bridges, H.R.,Grba, D.,Hirst, J. (deposition date: 2020-09-29, release date: 2021-02-03, Last modification date: 2021-02-10)

• Primary citation: Yin, Z.,Burger, N.,Kula-Alwar, D.,Aksentijevic, D.,Bridges, H.R.,Prag, H.A.,Grba, D.N.,Viscomi, C.,James, A.M.,Mottahedin, A.,Krieg, T.,Murphy, M.P.,Hirst, J.; Structural basis for a complex I mutation that blocks pathological ROS production.; Nat Commun, 12:707-707, 2021; PubMed: 33514727; DOI: 10.1038/s41467-021-20942-w

Experimental method

ELECTRON MICROSCOPY (3.17 Å)