7AHJ

Crystal structure of PPARgamma V290M mutant ligand binding domain in complex with farglitazar

Summary for 7AHJ

• Entry DOI: 10.2210/pdb7ahj/pdb
• Descriptor: Peroxisome proliferator-activated receptor gamma, 2-(2-BENZOYL-PHENYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACID (3 entities in total)
• Functional Keywords: nuclear receptor, nuclear protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 63395.68

Authors

Schoenmakers, E.,Schwabe, B.T.W.,Fairall, L.,Chatterjee, K.,Schwabe, J.W.R. (deposition date: 2020-09-24, release date: 2020-10-14, Last modification date: 2024-01-31)

• Primary citation: Schoenmakers, E.,Schwabe, B.T.W.,Fairall, L.,Chatterjee, K.,Schwabe, J.W.R.; Crystal structure of PPARgamma V290M mutant ligand binding domain in complex with farglitazar; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)